HLA-A*68
نویسندگان
چکیده
منابع مشابه
Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor
HLA-A*6801 exhibits several unusual features. First, it is known to bind weakly to CD8 due to the presence of an A245V substitution in the alpha3 domain. Second, it is able to accommodate unusually long peptides as a result of peptide 'kinking' in the binding groove. Third, CD8+ cytotoxic T lymphocytes that recognise HLA-A*6801-restricted antigens can tolerate substantial changes in the peptide...
متن کاملFunctional and biophysical characterization of an HLA-A[ast]6801-restricted HIV-specific T cell receptor
HLA-A*6801 exhibits several unusual features. First, it is known to bind weakly to CD8 due to the presence of an A245V substitution in the a3 domain. Second, it is able to accommodate unusually long peptides as a result of peptide 'kinking' in the binding groove. Third, CD8 cytotoxic T lymphocytes that recognise HLA-A*6801-restricted antigens can tolerate substantial changes in the peptide sequ...
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A random sample of 500 healthy unrelated subjects from Esfahan province were HLA typed for A, 8 and C locus antigens. The lymphocytes were separated from 5 ml of whole peripheral blood and were typed for HLA _ A, 8 and C by using the standard two stage microlymphocytotoxicity NIH technique. The findings suggest that in the study population, frequency of HLA-Al' A2, A3, Ag HLA-8s, 83S and HLA-CW...
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ژورنال
عنوان ژورنال: AIDS
سال: 2013
ISSN: 0269-9370
DOI: 10.1097/qad.0b013e32836146cd